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Mosbacher Kolloquium 2025:
AI-driven (r)evolution in structural biology & protein design

MARCH 20TH - 22ND 2025 | Mosbach/Baden, Germany

Birte Höcker /Bayreuth
Ina Koch /Frankfurt am Main
Janosch Hennig /Bayreuth

early registration: January 31, 2025
poster abstracts: January 31, 2025


Keystone Symposia Meeting:

Computational Design and Modeling of Biomolecules

MARCH 14TH - 17TH 2023 | Fairmont Banff Springs, Banff, AB, Canada

Scientific Organizers: Tim Whitehead, Nir London, Roberto A. Chica and Birte Höcker

The scientific community is increasingly able to predict and design three-dimensional structures of proteins, RNA, macromolecular complexes, and biomolecule-ligand interactions with atomic accuracy. This biomolecular design and modeling interdisciplinary field has impacted fields as diverse as immunology, nanotechnology, biocatalysis, cellular and molecular engineering, drug delivery, vaccinology, and drug discovery. These disparate fields are underpinned by continuing advances in the design and predictive modeling of biomolecules and biomolecular assemblies.

This conference was intended to bring the worldwide community of protein designers and modelers together to discuss recent advances. This program is topical as the field of protein design has moved from toy challenges to solving real-world problems. It was important to include computational design and modeling as its own conference as no other venue exists to bring the entire worldwide community to one location. In this watershed moment in the life of the field, this meeting can unite the global community of molecular modelers to build on these successes and push forward as a community to expand the field by diversifying our methods, approaches and ideas. In addition, the field of molecular modeling is naturally positioned to implement and integrate concepts and methodologies in deep learning and artificial intelligence. The huge recent spike in interest in such methods gave this conference a great opportunity to spearhead these developments.

Apfed 22

APFED22: Advances in Protein Folding Evolution and Design:
Fostering protein research in Europe

APRIL 6TH - 8TH 2022 | Bayreuth Campus

Most conferences of interest to the protein-design community are hosted outside of Europe. Despite this, there is a burgeoning network of academics within European institutions and we therefore decided to host a conference in Germany. Through a University of Bayreuth funding scheme and a grant from the DFG, three PostDocs of our group were fortuitously able to realise this conference about protein folding, protein evolution and protein design.


Mohammed AlQuraishi, Harvard Medical School, Boston (USA)

Patrick Barth, École Polytechnique Fédérale de Lausanne (Switzerland)

Manajit Hayer-Hartl, Max Planck Institute of Biochemistry, Martinsried (Germany)

Georg Hochberg, Max Planck Institute for Terrestrial Microbiology, Marburg (Germany)

Klara Hlouchova, Charles University, Prague (Czech Republic)

Petra Imhof, Friedrich-Alexander Universität Erlangen-Nürnberg, (Germany)

Ina Koch, Goethe-Universität Frankfurth a.M. (Germany)

Nobuyasu Koga, Institute for Molecular Science, Okazaki (Japan)

Sílvia Osuna, Institute of Computational Chemistry and Catalysis (IQCC), Girona (Spain)

José Manuel Sánchez Ruiz, University of Granada (Spain)

Joanna Slusky, University of Kansas (USA)

Arnout Voet, Katholieke Universiteit Leuven (Belgium)

Renko de Vries, Wageningen University (Netherlands)

Christopher Wood, The University of Edinburgh (UK)

Cathleen Zeymer, Technical University of Munich (Germany)

Susan Marqusee, University of California, Berkeley (USA)

Additional material:

Predictive Reagent Antibody Replacement Technology:
PRe-ART Symposium 2019

SEPTEMBER 18TH - 19TH 2019 | Bayreuth Campus

The PRe-ART and PRe-ART-2T projects take an interdisciplinary approach to establish a novel detection system. To exchange ideas and gather new perspectives on our challenge we had the opportunity to host a scientific symposium in Bayreuth. We are proud of inviting leading voices of the protein design, protein engineering and protein evolution communities.


Bruce Donald, Duke University, USA

Christophe Jung, LMU, Germany

Dafydd Jones, Cardiff University, UK

Dek Woolfson, Bristol University, UK

Johan Aqvist, Uppsala University, Sweden

Lynne Regan, Edinburgh University, UK

Ora Furman, Hebrew University, Israel

Roberto Chica, Ottawa University, Canada

Webmaster: Univ.Prof.Dr. Birte Höcker

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